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'<br>Melanotan 2 is a popular over the counter medication that can be found in different drugstores and cosmetic clinics. The main active ingredient is hydroquinone or to give it its official name Finasteride, which is known to be a melanocortin receptor kinase inhibitor. The melanocortin is responsible for inhibiting the production of melanin and its growth in the dermis. The melanocytes, which are responsible for melanin production are located in the basal layer of the epidermis. The melanocytes respond to the presence of melanoma. The melanotan contains enzyme called melanocortinocorticoid which is responsible for stimulating melanin growth.<br><br><br>There are two major classes of medications for the treatment of acne. Acne-Cortacea is a broad category while Dermatology, Melanotan-Cortical is a more precise one. The main active ingredients of Dermatology drugs are trichloroacetic acid, adapalene, and retinoids, which all aim at targeting the melanocytes and inhibiting melanoma production. Melanotan-Cortical on the other hand only affects the cells in the uppermost layers of the epidermis where as the trichloroacetic acid can reach all the way down to the basement membrane. This formulation allows for better penetration and therefore faster effects.<br><br><br>The question that arises from this is whether the melanoma, which targets the pigment cells, produces adverse side effects. Melanotan has been used for quite some time and has been approved by the FDA in 1982. The first reported case of skin pigmentation was associated with the administration of disfunzione erettile melanotan ii. Since then, there have been reports of benign conditions and severe complications resulting from its use. The melanoma association was further substantiated when a patient exposed to disfunzione-treated melanoma died from complications caused by the drug.<br><br><br>Dermatology drugs are used for various disorders. Among them is a melanoma named prostatitis, which belongs to the inflammatory type. It is characterized by inflammation of the hair follicles, usually the ones in the posterior portion of the trunk and the surrounding areas. The inflammation can be the consequence of trauma as well as an allergic reaction.<br><br><br>Another condition treated by this drug is the acute transfer of pigment cells from the dermal layers to the epidermis. This condition is called as the photo pigmentary follicular transfer disorder (PPT or photo pigmentary follicular transfer disorder). Melanotan treatment thus treats photo-transformed cells, which are also known as the primary cells. These are also divided into two major types: the tosone types (tosano-converted or tosone-type cells) and the non-tosano-converted cells.<br><br><br>The melanoma drug has been shown to reduce the melanin content in the skin by more than 40% when taken orally in the raccoon clover extract formula. However, the studies concluded that the result seen in these studies was not conclusive because the raccoon clover extract also contains other constituents, which might affect the results of the study. Other studies have also found reduced melanin levels in mice treated with the melanoma. Similarly, studies using the tosone types of melanocytes in vitro showed that the drug reduced the proliferation of melanocytes (males & females) and the function of melanocytes (pigment producing cells).<br><br><br>Clinical trials using a purified form of the tone called Insufficienza erettile melanotan 2 mg, which is extracted from the insufficienza grapefruit, have also shown better results in reducing the pigmentation of the skin. However, clinical studies using this melanized form of the drug have only been performed in Japan and Korea. There are no known side effects of Insufficienza in humans. One significant limitation of this melanoma drug is that it is unable to penetrate the epithelial layer of the skin which prevents further penetration of melanocortin.<br><br><br>Clinical studies using the vitamin E, alla propantia, alla prostrating, alla silica and allaflavin acetate (Alli, Vysis, Actonel) have also shown melanotan production reduction. Vitamin E has been found to be [http://www.supplybenzocaine.co.uk/news/42-en.html more] effective in the stimulation of melanocyte generation than other compounds such as the aforementioned four types of melanocytes melanocortin, melanocyte stimulating hormone (MSH), sanyozyme Q10 and lecithin. These vitamins have the ability to stimulate cellular metabolism which allows increased production of melanoma cells (keratinocytes). They are able to achieve this by activating cellular oxidative pathways. Some of these vitamin E antioxidants include selenium, flavonoids, lipoic acid, bioflavonoids, proanthocyanidins, quercetin, lycopene, lutein, hesperetin, hesperidin, totecetine and vitamin E.<br>'